Dr Nortley deciphered the mechanism by which brain blood flow becomes reduced in the early stages of Alzheimer's disease. This had puzzled the scientific community for many years.
His findings attracted worldwide interest and he has been invited to speak internationally on his research.
"Science", also widely referred to as Science Magazine, is the academic journal of the American Association for the Advancement of Science and one of the world's top academic journals.
"Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes."
Hope of a way to treat Alzheimer's as scientists find the memory-robbing disorder "may be caused by blood vessels in the brain being squeezed"
THE MEDICAL EXPRESS
ALZHEIMER'S RESERCH FOUNDATION, ALZINFO.ORG
‘Squeezed’ blood vessels in the brain may contribute to Alzheimer's onset
SQUEEZING THE BRAIN’S BLOOD SUPPLY
Researchers at University College, London have discovered a reason for restricted blood flow—they’ve shown that amyloid beta can cause the cells surrounding capillaries to contract and to squeeze the vessels, narrowing them (Nortley et al, 2019).